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Vol.17 - No.2 (April 2026)

Original Article

Clinical impact of a rapid-acting insulin bolus at the initiation of continuous insulin infusion therapy in patients with hyperglycemic crisis: a propensity score-matched analysis

Yuichiro Iwamoto, Tomohiko Kimura, Takashi Itoh, Toshitomo Sugisaki, Kazunori Dan, Hideyuki Iwamoto, Yoshiro Fushimi, Junpei Sanada, Masashi Shimoda, Shuhei Nakanishi, Kohei Kaku & Hideaki Kaneto 05 April 2026

Case Report

Acute onset of neovascular age-related macular degeneration after initiation of tirzepatide

Kohzo Takebayashi, Yurina Iemura, Mototaka Yamauchi, Kenji Hara, Takafumi Tsuchiya, Shigeki Machida & Koshi Hashimoto 05 April 2026

Original Article

Functional category, physical frailty, and sarcopenia in older adults with diabetes mellitus: a cross-sectional study

Takuya Omura, Taiki Sugimoto, Ayumi Sugie, Mariko Ban, Ayano Toda, Seiya Tanaka, Tomoyasu Kinoshita, Naoki Yamauchi, Makio Tanabashi, Yoshiharu Ohshima, Naoki Takashi, Shosuke Ohtera & Takahiro Kamihara 05 April 2026

Original Article

Anthropometry-adjusted TyG indices improve insulin resistance estimation: an exploratory euglycemic–hyperinsulinemic clamp study in Japanese adults without diabetes

Natsu Otowa-Suematsu, Tomoaki Nakamura, Hiroshi Miura, Tomoko Yamada, Marika Nishisaka, Hayato Fukumitsu, Yukari Katsura, Yasuko Morita, Shun-Ichiro Asahara & Kazuhiko Sakaguchi 05 April 2026

Original Article

Heat shock protein 72 (HSP72) modulates glucagon secretion via JNK inhibition in pancreatic α-cells

Takuro Watanabe, Tatsuya Kondo, Rintaro Yoshizumi, Nobukazu Miyakawa, Sayaka Kitano, Mary Ann Suico, Miki Sato, Masaji Sakaguchi, Motoyuki Igata, Takeshi Matsumura, Hirofumi Kai, Eiichi Araki & Naoto Kubota 29 March 2026

Original Article

Teleguidance by physiotherapists maintains the quality of life in older patients with diabetic polyneuropathy: subanalysis of the TelePhysioT2D trial

Takuo Nomura, Hiroaki Kataoka, Hiroyuki Oka & Yukio Ikeda 23 March 2026

Original Article

Association between sarcopenia and the presence of diarrhea or constipation in individuals with type 2 diabetes: a cross-sectional study

Genki Kobayashi, Yoshitaka Hashimoto, Shinta Yamamoto, Masahide Hamaguchi & Michiaki Fukui 17 March 2026

Original Article

Retrospective real-world database study to examine the prevalence and incidence of cardiovascular diseases and medication prescription in Japanese patients with type 2 diabetes

Mitsuhisa Komatsu, Hiroshi Kobayashi, Satoshi Tsuboi & Hirotaka Watada 17 March 2026

Original Article

Baseline characteristics of patients with type 1 and type 2 diabetes in the Asahi Diabetes Complications Study (Asahi Study): a clinic-based prospective observational study

Yoko Yoshida, Yukiko Onishi, Tetsuya Kubota, Toshiko Takao, Tazu Tahara, Masahiko Iwamoto, Shoji Kawazu, Yasuhiko Iwamoto, Mitsuhiko Noda & Masato Kasuga 09 March 2026

Case Report

A case of type 2 diabetes with spinal and bulbar muscular atrophy treated with oral semaglutide while sparing muscle reduction for two years: a case report with literature review

Yuto Nakano, Shuhei Morita, Nobuyuki Nishi, Masanori Kita, Naoki Shimo, Ken Takeshima, Yasushi Furukawa & Taka-aki Matsuoka 09 March 2026

Case Report

Insulinoma complicated with hypergastrinemia in a subject with type 2 diabetes mellitus: a case report

Hideyuki Iwamoto, Takatoshi Anno, Yuichiro Iwamoto, Fumiko Kawasaki, Kohei Kaku & Hideaki Kaneto 09 March 2026

Original Article

The combination of the D-dimer/fibrinogen ratio and the CHA2DS2-VA score is exploited for the prediction of carotid atherosclerosis in patients with type 2 diabetes mellitus: a retrospective cohort study

Shikai Wang, Zhenzhen Long, Junli Zhang, Lu Jiang & Lijun Hou 25 February 2026

Original Article

Glucagon and insulin prescribing trends and cost implications in Japan: a 10-year analysis using the National Database Open Data Japan

Tomoyuki Saito, Kazutoshi Fujibayashi, Hiroshi Ohtsu & Yuichiro Yano 25 February 2026

Review Article

Investigational treatments of β-cell failure and replacement

Domenico Accili, Wen Du, Takumi Kitamoto, Wendy McKimpson, Jinsook Son & Hitoshi Watanabe 17 February 2026

Original Article

Hypoglycemia problem-solving ability as a key predictor of severe hypoglycemia: a machine learning approach in adults with type 1 diabetes

Naoki Sakane, Ken Kato, Sonyun Hata, Erika Nishimura, Rika Araki, Kunichi kouyama, Masako Hatao, Yuka Matoba, Yuichi Matsushita, Masayuki Domichi, Akiko Suganuma, Seiko Sakane, Takashi Murata & Fei Ling Wu 17 February 2026

Review Article

RFX6 expression is central to the development and function of the neuroendocrine compartments of the pancreas and intestine and strongly affects diabetes risk

Thomas S. R. Bate, Yuanhao Huang, Xin Luo, Diane C. Saunders, John T. Walker, Vivek Rai, Stephen C. J. Parker, Jie Liu & Marcela Brissova 17 February 2026

Original Article

Impact of diabetes care discontinuation on healthcare costs in older patients with type 2 diabetes: a retrospective study using medical claims data

Akira Kurishima, Kenjiro Imai, Yusuke Kuwai, Mari Irie & Yoshiharu Fukuda 06 February 2026

Original Article

Identification of severe hypoglycemia in adults with type 1 diabetes using CGM-based machine learning: evidence from the FGM-Japan study

Naoki Sakane, Yushi Hirota, Akane Yamamoto, Junnosuke Miura, Hiroko Takaike, Sari Hoshina, Masao Toyoda, Nobumichi Saito, Kiminori Hosoda, Masaki Matsubara, Atsuhito Tone, Satoshi Kawashima, Hideaki Sawaki, Tomokazu Matsuda, Masayuki Domichi, Akiko Suganuma, Seiko Sakane & Takashi Murata 01 February 2026

Update: May 7, 2026